科研情况: ◉ 主要研究方向: 1、小分子及纳米探针的设计、合成及其在检测分析中的应用; 2、智能药物的构建与应用。 ◉ 近5年科研项目: 1、国家自然科学基金青年项目,2023.01-2025.12,在研,主持 2、湖南省自然科学基金青年项目,2022.01-2024.12,在研,主持 3、区域遗传性出生缺陷防控研究湖南省重点实验室开放基金,在研,主持 4、湖南省教育厅一般项目,结题 5、化学生物传感与计量学国家重点实验室开放基金,结题 ◉ 近5年代表性的科研论文与专利: (1)Roumei Li, Xuan Lan, Xiaowen Liu, Cheng Xie, Bin Yuan, Junbin Li*, Zenghui Mao*, Zhihe Qing*. An activatable formaldehyde donor with high contrast bioluminescence to monitor its release. Sensors and Actuators: B. Chemical, 2024, 414, 135949. (SCI一区) (2)Junbin Li, Lifei Song, Weiguo Hu, Qin Zuo, Roumei Li, Min Dai, Yibo Zhou, and Zhihe Qing*. A Reversible Fluorescent Probe for In Situ Monitoring Redox Imbalance during Mitophagy, Analytical Chemistry, 2023, 95, 36, 13668–13673. (SCI一区) (3) Jingxuan Zhu, Qiaozhen Ye, Shuai Xu*, Haixia Li, Junbin Li* and Hongwen Liu*, β-galactosidase activatable chemiluminescent probe for in vivo imaging and point-of care test, Sensors and Actuators: B. Chemical, 2023, 396, 134521. (SCI一区) (4) Junbin Li, Na Wang, Mengyi Xiong*, Min Dai, Cheng Xie, Qianqian Wang, Ke Quan, Yibo Zhou*, and Zhihe Qing*. A Reaction-Based Ratiometric Bioluminescent Platform for Point-of-Care and Quantitative Detection Using a Smartphone, Analytical Chemistry, 2023, 95, 18, 7142–7149. (SCI一区) (5) Junbin Li, Ying Zhou, Lifei Song, Sheng Yang, Qianqian Wang, Yibo Zhou, Xiaobing Zhang, Zhihe Qing*, Ronghua Yang*. A brain-targeted near-infrared nanobeacon for in situ monitoring H2S fluctuation during epileptic seizures. Analytical Chemistry, 2022, 94, 15085-15092. (SCI一区) (6) 李俊彬; 卿志和; 熊梦仪; 汪娜; 一种比率生物发光可视化检测次氯酸的荧光探针及其制备与应用, 2023-11-10, 中国, ZL 2022 1 1252111.2 (发明专利) |